Pharmaceutical: Ingredientpharm provides innovative drug carriers by changing the physical properties of existing excipients.
Apr 05, 2022. Register for the online seminar recordings: “Functional Tartaric Acid Pellets in Modern Formulation Challenges”.
Speakers: Philippe Tschopp, Raja Subburayalu, with kind session chair by Marco Resciniti.
Sponsoring companies: Glatt Group, ingredientpharm, PHARMATRANS SANAQ AG, HARKE GROUP.
Target group: for Manager working in Pharmaceutical Technology and Formulation Sciences.
Register here: Webinar-Registrierung – Zoom
Abstract: Functional Tartaric Acid Pellets in Modern Formulation Challenges
Multi particulate modified release dosage forms, where the drug shows pH dependent solubility, require an acidic in-situ microenvironment to improve solubility, release, and absorption. Present generic formulations focus on these so-called BSC Class IV drugs. The Role of Reverse Engineering is thereby an efficient key tool in the development of generic formulations. A Case study presents latest state-of-the-art achievements.
The live webcast will bring interesting case provided by Pharmatrans SANAQ® and technically discussed and presented by Philippe Tschopp, Business Development at Glatt Pharmaceutical Services in Germany and Dr. Raja Subburayalu, consultant in Manufacturing Science and Technology Transfer for Zydus Cadila Healthcare Limited, based in Ahmedabad, Gujarat, India.
Dr Subburayalu will explore how present generic formulations focus on so-called BSC Class IV drugs in which multi particulate modified release dosage forms, where the drug shows pH dependent solubility, require an acidic in-situ microenvironment to improve solubility, release, and absorption.
They will highlight how Reverse Engineering using TAP® can form an efficient key tool in the development of generic formulations. The webinar will feature a case study illustrating latest state-of-the-art achievements.
Register here for the online seminar recording
ingredientpharm extends Tartaric Acid Pellets (TAP®) portfolio adjusting to future generic drug formulations on BCS Class IV drugs. TAP are starter pellets for generic drugs, BSC Class IV.
BSC Class IV drugs have low solubility and low permeability properties. Typical drugs are Verapamil HCL, Propiverine HCL, Papaverine, Dipyridamole, or Dabigatran. Functional TAP® starter pellets increase the local solubility of these drugs.
Extending the diversity of TAP® starter pellets, ingredientpharm is now offering standard sizes and special sizes between 100 µm and 1000 µm.
A new information pool for MCC pellets displays scientific work performed with CELLETS®. Starter pellets made of Microcrystalline Cellulose (MCC) are traditionally called CELLETS® at ingredientpharm. MCC pellets do not only play a major role in modern pharmaceutical formulations for oral drugs, but are frequently investigated in scientific research and industrial studies.
This list of scientific publications serves easy and fast access to current research and investigation on modern formulations for oral drugs and pellet technologies.
ingredientpharm announces that TAP Registration for Chinese Market is approved. The new Drug Master File for TAP® following ChP regulations enables to use drug formulations containing TAP® to be marketed in one of the world largest pharmaceutical markets.
TAP® is a pelletized excipient made of 100% Tartaric Acid. These functional pellets modify the local environment and increase the solubility of BSC Class IV drugs tremendously. TAP® pellets are available in different sizes from 100 µm to 1000 µm and corresponds to monographs Ph.Eur., USP/NF, JP/JPE, ChP.
See: product details