Ibuprofen DC100 – made for direct compression
Ibuprofen DC100 (Ph. Eur.) for direct compression consists of 100% Ibuprofen drug substance without any additional excipients. The particles are spherically shaped, making Ibuprofen DC100 the only directly compressible form of Ibuprofen. Its unique shape and surface structure provide distinct product characteristics and enable a wide range of applications.
As a DC-grade material, Ibuprofen DC100 exhibits excellent compression properties, allowing the manufacture of tablets with exceptionally high drug loads. Moreover, its spherical shape and low attrition facilitate efficient coating with functional polymers, making it suitable for sustained-release formulations such as capsules or pellet tablets.
In addition, the smooth surface and low porosity of Ibuprofen DC100 spheres allow convenient layering with taste-masking coatings. This property enables the production of easy-to-swallow, taste-masked products, including sachets and orally dispersible tablets (ODTs).
Expert’s opinion
Ibuprofen DC100 (Ph. Eur.) is a granular form of Ibuprofen and can thus substitute the drug in pharmaceutical formulations – yielding an efficient process and coating options.
Formulation without Ibuprofen DC 100 undergo further process steps, increasing uncertainity, risk of failure, and process time.
Formulation with Ibuprofen DC 100 minimzes process steps, increasing optimizing process time, and formulation safety.
Advantages at a glance
100% pure Ibuprofen for easy formulations.
- Simplifying drug formulations
- 100% pure Ibuprofen for easy substitution in dossiers
- 0% additional excipients
- Controlled pellet size
- GMP quality made in Germany
- Substitutes risks and critical compression behavior of Ibuprofen granules
Find further technical specifications in the product information.
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