Ibuprofen DC100 – made for direct compression
Ibuprofen DC100 (Ph. Eur / USP-NF) for direct compression is made of 100% Ibuprofen drug substance without further excipients. The particles are spherically shaped. Thus, Ibuprofen DC100 becomes the unique directly compressible form of Ibuprofen. Due to its shape and surface structure, Ibuprofen DC100 provides unique product characteristics offering a wide range of applications.
Ibuprofen DC100 may serve as DC grade with excellent compression properties for the manufacture of tablets with an exceptionally high drug load.
Owing to the spherical shape and low attrition, Ibuprofen DC100 particles can be efficiently coated with functional polymers to prepare sustained release drug products as capsules or pellet tablets.
Because of the smoothness and low porosity, Ibuprofen DC100 spheres can be conveniently layered with taste masking coatings to prepare easy to swallow taste masked drug products such as sachets or oral dispersible tablet (ODT) preparations.
Expert’s opinion
Ibuprofen DC100 (Ph. Eur / USP-NF) is a special physical form of Ibuprofen and can thus substitute the drug in pharmaceutical formulations – yielding an efficient process and coating options.
Formulation without Ibuprofen DC 100 undergo further process steps, increasing uncertainity, risk of failure, and process time.
Formulation with Ibuprofen DC 100 minimzes process steps, increasing optimizing process time, and formulation safety.
Advantages at a glance
100% pure Ibuprofen for easy formulations.
- Simplifying drug formulations
- 100% pure Ibuprofen for easy substitution in dossiers
- 0% additional excipients
- Controlled pellet size
- GMP quality made in Germany
- Substitutes risks and critical compression behavior of Ibuprofen granules
Find further technical specifications in the product information.
ingredientpharm
ingredientpharm